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產(chǎn)品詳情
  • 產(chǎn)品名稱:G-2andS-PhaseExpressed1(GTSE1)(MiddleRegion)Peptide

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G-2andS-PhaseExpressed1(GTSE1)(MiddleRegion)Peptide
詳情介紹:
Blocked Antibody anti-GTSE1 antibody (G-2 and S-Phase Expressed 1) (Middle Region) (ABIN2775434)
Characteristics This is a synthetic peptide designed for use in combination with anti-GTSE1 antibody (Catalog #: ARP42471_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.

Alias Symbols: B99

Protein Interaction Partner: USP11

Protein Size: 720
Molecular Weight 76 kDa
Gene ID 51512
NCBI Accession NM_016426, NP_057510
UniProt Q9NYZ3
Research Area DNA/RNA, Cell Cycle, Apoptosis/Necrosis, Cancer
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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