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Background
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NCBP1 is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CBP80, MGC2087, NCBP, Sto1
Protein Interaction Partner: EIF4G1,EIF4G2,NCBP2,STAU1,BNIP1,BNIP3,EIF4G1,EIF4G2,HNRNPF,HNRNPH1,NCBP2,RNF40,RPS6KB1,SNRPA1,STAU1,BNIP1,BNIP2,BNIP3,EIF4G1,HNRNPF,HNRNPH1,NCBP2,RNF40,SRSF9
Protein Size: 790
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